S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin Sodium Salt

产品名称：S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin Sodium Salt

产品描述：

QYD242100

Chemical Name:S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin Sodium Salt

Synonyms
(3R,5S,6E)-7-(4-(4-Fluorophenyl)-2-(2-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-2-hydroxy-N-methylethylsulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic Acid Sodium Salt； Rosuvastatin Impurity E (EP) Sodium Salt； (3R,​5S,​6E)​-5-​Dihydroxy-​7-​[4-​(4-​fluorophenyl)​-​2-​[[[2-​[4-​(4-​fluorophenyl)​-​6-​(1-​methylethyl)​-​2-​[methyl(methylsulfon​yl)​amino]​-​5-​pyrimidinyl]​-​2-​hydroxyethyl]​sulfonyl]​methylamino]​-​6-​(1-​methylethyl)​-​5-​pyrimidinyl]​-​3 6-​heptenoic Acid Sodium Salt； Sodium (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-2-hydroxy-N-methylethyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate/Rosuvastatin Impurity E

Impurity
Rosuvastatin Impurity E

Alternate CAS #
2226413-61-0

Molecular Formula:C38H45F2N6NaO9S2

Molecular Weight :854.92

Category :Standards； Pharmaceutical/API Drug Impurities/Metabolites；

Applications
S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin Sodium Salt is a salt analog of S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin (CAT# D231090), which is a dimerized impurity of Rosuvastatin (CAT# R700500), a selective, competitive HMG-CoA reductase inhibitor. S-Demethyl S-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-hydroxyethyl Rosuvastatin can be used in the development and validation of a hydrophilic interaction liquid chromatography method for the quantitation of impurities in fixed-​dose combination tablets containing rosuvastatin and metformin.

References
Machairas, G., et al.: Talanta, 183, 131-141 (2018)； Salih, O. S.: Int. J. Pharm. Pharm. Sci., 7, 166 (2015)； Ramu, A., et al.: Asian J. Chem., 25, 5340 (2013)

规格：mg/g/kg

配送：惯例下常温包邮

包装：袋装

厂家：西安齐岳生物科技有限公司

运输说明:

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低温产品:低温产品运输过程中加装冰袋运输。

常温产品:常温产品运输过程中无需加冰或者特殊包装

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