活性氧Isoquercetin,482-35-9
产品名称:活性氧Isoquercetin,482-35-9
产品描述:
产品名称:活性氧Isoquercetin,482-35-9
产地:西安
规格:1mg 5mg 10mg
纯度:99%
用途:仅用于科研
状态:固体/粉末
储藏条件:冷藏-20℃
温馨提示:仅用于科研,不能用于人体实验!
说明:提供使用说明,核磁图谱,包装,价格,产地,制备方法,应用,稳定性,溶解度,简单合成等各种信息
Isoquercetin is a flavonoid that has been isolated from A. venetum and has diverse biological activities, including antiviral, anti-apoptotic, and neuroprotective properties.1,2,3 It reduces viral titers of H5N1 influenza isolates by 79.66% in a plaque assay when used at a concentration of 1 ng/ml.1 It inhibits apoptosis, increases cell viability, and decreases the level of reactive oxygen species (ROS) in an oxygen-glucose deprivation/reoxygenation assay when used at concentrations of 25, 50, and 100 µg/ml in primary rat hippocampal neurons and decreases TNF-α-induced cell death in primary mouse hepatocytes (IC50 = 37.5 µM).2,3 Isoquercetin (50 mg/kg) is neuroprotective in a rat model of middle cerebral artery occlusion (MCAO), reducing infarct volume and neurological symptoms, as well as increasing hippocampal expression of Nrf2 and phosphorylation of ERK1/2.
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