活性氧Nitrotyrosine Polyclonal Antibody，3-Nitrotyrosine
产品名称：活性氧Nitrotyrosine Polyclonal Antibody，3-Nitrotyrosine
产品描述：
产品名称：
活性氧Nitrotyrosine Polyclonal Antibody，3-Nitrotyrosine
产地：西安
规格：1mg 5mg 10mg
纯度：99%
用途：仅用于科研
状态：固体/粉末
储藏条件：冷藏-20℃
温馨提示：仅用于科研，不能用于人体实验！
说明：提供使用说明，核磁图谱，包装，价格，产地，制备方法，应用，稳定性，溶解度，简单合成等各种信息
Nitrotyrosine is a post-translational modification that is formed by the nitration of tyrosine.1 Under conditions of oxidative stress, tyrosine is oxidized by reactive oxygen species (ROS) or, in the presence of hydrogen peroxide and nitrite, by myeloperoxidase (MPO) to yield a tyrosine radical that reacts with reactive nitrogen species (RNS), such as nitric oxide or peroxynitrite, to form nitrotyrosine. It exists in a free or protein-bound form and is commonly used as a marker of nitrosative or oxidative stress.2 Nitrotyrosine residues have been found in a variety of proteins, including LDL, surfactant protein A, angiotensin II, and human and bovine serum albumin.3 Free nitrotyrosine production induced by peroxynitrite is inhibited by the polyphenols epicatechin gallate, gallic acid, catechin, or epicatechin in cell-free assays, as well as in aortic rings isolated from normotensive and spontaneously hypertensive rats administered the antioxidant N-acetyl-cysteine (NAC; Item No. 20261).4,5 Nitrotyrosine levels are increased in the affected tissues of numerous pathological conditions, including atherosclerosis, cancer, ulcerative colitis, Alzheimer's disease, and Parkinson's disease.3 Autoantibodies that recognize nitrotyrosinated proteins are increased in the synovium of patients with rheumatoid arthritis and are positively correlated with joint and tendon inflammation.1 Cayman's Nitrotyrosine Polyclonal Antibody can be used for Western blot (WB) applications.
相关产品：
活性氧Nitrotyrosine Monoclonal Antibody - Biotinylated，3-Nitrotyrosine
活性氧Nitrotyrosine Monoclonal Antibody，3-Nitrotyrosine
活性氧Temoporfin，122341-38-2
编辑：XAQYBIO HAO，2023年3月27日。
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公司介绍：
西安齐岳生物科技有限公司是集化学科研和定制与一体的高科技化学公司。业务范围包括化学试剂和产品的研发、生产、销售等。涉及产品为通用试剂的分销、非通用试剂的定制与研发，涵盖生物科技、化学品、中间体和化工材料等领域。
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