Schisandrol B
作者：齐岳
发布时间：2023-09-14
09:02:09
点击数：
产品名称：Schisandrol B
产品描述：
| 植物来源 | 天然产物 > 五味子科 > 五味子属 |
| 结构类型 | 天然产物 > 木脂素 |
| 产品描述 | 1. Gomisin A may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Gomisin A has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Gomisin A induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Gomisin A significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation. |
| 别名 | Wuweizi alcohol-B, TJN-101, Gomisin A, Gamma-Schisandrin, 五味子醇乙, 戈米辛A, Schizandrol B, Besigomsin |
| 分子量 | 416.47 |
| 分子式 | C23H28O7 |
| CAS No. | 58546-54-6 |
存储
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 50 mg/mL (120.06 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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