GC7 Sulfate
作者：齐岳
发布时间：2023-09-13
17:28:13
点击数：
产品名称：GC7 Sulfate
产品描述：
| 产品描述 | GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity. |
| 靶点活性 | Spermidine:10 nM(ki) |
| 体外活性 | Cell cycle analysis show that GC7 Sulfate reduces the CHO-K1 cell population in the G1-phase of the cell cycle by 42% and increases the number of cells in the S-phase by 44%. Furthermore, GC7 Sulfate inhibited the growth of H9 cells in a concentration-dependent manner. While 1 μM GC7 Sulfate had no significant effect on H9 cell proliferation, inhibition of growth became evident with 3 μM GC7 Sulfate. At 10 μM GC7 Sulfate, H9 cell growth was completely blocked within 1 or 2 days after the addition of the drug[1]. |
| 分子量 | 270.35 |
| 分子式 | C8H22N4O4S |
| CAS No. | 150417-90-6 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
H2O: 2.7 mg/mL (10.0 mM),Need ultrasonic and warming
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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公司介绍：
西安齐岳生物科技有限公司是集化学科研和定制与一体的高科技化学公司。业务范围包括化学试剂和产品的研发、生产、销售等。涉及产品为通用试剂的分销、非通用试剂的定制与研发，涵盖生物科技、化学品、中间体和化工材料等领域。
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