Ligustilide
产品名称:Ligustilide
产品描述:
植物来源 | 天然产物 > 伞形科 > 当归属 |
产品描述 | 3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis. |
体外活性 | To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide . |
分子量 | 190.24 |
分子式 | C12H14O2 |
CAS No. | 4431-01-0 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 1.9 mg/mL (10 mM),Need ultrasonic
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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