Barlerin
作者：齐岳
发布时间：2023-09-07
09:22:15
点击数：
产品名称：Barlerin
产品描述：
| 植物来源 | 天然产物 > 茜草科 > 栀子属 |
| 产品描述 | 8-O-Acetylshanzhiside methylester has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ elevation and caspase-3 activity, and improvement of mitochondrial energy metabolism.8-O-Acetylshanzhiside methylester can increase angiogenesis and improve functional recovery after stroke.8-O-Acetylshanzhiside methylester has protective effects on experimental myocardial ischemia injury, the effects might be due to block of myocardial inflammatory cascades through an HMGB1-dependent NF-κB signaling pathway.8-O-Acetylshanzhiside methylester protects diabetic brain against I/R injury by alleviating diabetic cerebral I/R injury and attenuating blood–brain barrier (BBB) breakdown, and its protective effects may involve HMGB-1 and NF-κB signalling pathway. |
| 别名 | 8-O-乙酰山栀苷甲酯, 8-O-Acetylshanzhiside methyl ester, ND01 |
| 分子量 | 448.42 |
| 分子式 | C19H28O12 |
| CAS No. | 57420-46-9 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 82 mg/mL(182.9 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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