Polyporenic acid C
作者：齐岳
发布时间：2023-08-28
09:04:40
点击数：
产品名称：Polyporenic acid C
产品描述：
| 植物来源 | 天然产物 > 多孔菌科 > 茯苓属 |
| 结构类型 | 天然产物 > 萜类 |
| 产品描述 | Polyporenic acid C shows inhibitory activity against human collagenase. |
| 体外活性 | Polyporenic acid C (PPAC) significantly reduced cell proliferation via induction of apoptosis as evidenced by sub-G1 analysis, annexin V-FITC staining, and increase in cleavage of procaspase-8, -3, and poly(ADP-ribose)-polymerase (PARP). However, unlike our previously reported lanostane-type triterpenoid, pachymic acid, treatment of cells with PPAC was not accompanied by disruption of mitochondrial membrane potential and increase in cleavage of procaspase-9. Further, PPC-induced apoptosis was inhibited by caspase-8 and pan-caspase inhibitors but not by a caspase-9 inhibitor. |
| 别名 | 猪苓酸C, 聚孔酸C |
| 分子量 | 482.69 |
| 分子式 | C31H46O4 |
| CAS No. | 465-18-9 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 60 mg/mL (124.3 mM),ultrasonic and warming and heat to 60°C
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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